Mayon Volcano has long been known for its perfect cone, violent eruptions, and postcard beauty. Now, Filipino scientists have found something far smaller in its volcanic soil that could carry serious medical promise.
Researchers from the University of the Philippines Los Baños found 30 bacterial isolates from soil samples collected in Malilipot, Albay, near Mt. Mayon. Thirteen showed antibiotic activity. One isolate, identified as Streptomyces sp. A1-08, stood out after showing activity against several harmful microorganisms and anti-colorectal cancer potential in laboratory testing.
The DOST reported the findings on August 3, 2021. The work was led by Asst. Prof. Kristel Mae P. Oliveros of UPLB’s Microbiology Division, with Albert Remus R. Rosana, Andrew D. Montecillo, Dr. Rina B. Opulencia, Arian J. Jacildo, Dr. Asuncion K. Raymundo, and the late Dr. Teofila O. Zulaybar also involved.
“We have high hopes of getting new and novel species because this is a less explored environment, a volcano,” Oliveros said. “We were totally surprised and excited.”
A1-08 drew closer attention after showing antagonistic effects on all test microorganisms, including methicillin-resistant Staphylococcus aureus, or MRSA, a bacteria known for resisting many antibiotics. That matters because drug-resistant infections keep pushing scientists to search for new sources of medicine.
The cancer-related finding also opened a hopeful research path. DOST said the crude extract showed low potency compared with doxorubicin, a proven chemotherapy drug. Oliveros explained that the material tested was still “a crude extract” and “still a complex mixture,” meaning its raw compounds can still be purified and studied further.
“Way forward, further studies should be made for us to establish that this novel species can likewise produce novel bioactive compounds,” Oliveros said.
For ordinary Filipinos, the discovery gives Mayon a new kind of power. Beneath soil shaped by eruptions, UPLB scientists found a living clue that could help guide future research on antibiotics and cancer-related treatments.
